heparin sodium injection GMP

Heparin sodium injection
Ampoules 2.0ml:5000IU;2.0ml:125000IU.
stable supply and credible quality.

Heparin is aheterogenous group of straight-chain anionic mucopolysaccharides, calledglycosaminoglycans, possessing anticoagulant properties. It is composed ofpolymers of alternating derivations of α-D-glucosamido (N-sulfated O-sulfatedor N-acetylated) and O-sulfated uronic acid (α-L-iduronicacid or β-D-glucuronic acid).

HEPARIN SODIUM INJECTION is a sterilepreparation of heparin sodium derived from porcine intestinal tissue,standardized for anticoagulant activity, in water for injection. It is intendedfor intravenous or deep subcutaneous administration. The potency is determinedby a biological assay using a USP reference standard based on units of heparinactivity per milligram.

For formulations preserved with benzylalcohol, each mL of the 1,000 and 5,000 USP units per mL preparations contains:heparin sodium 1,000 or 5,000 USP units; 9 mg sodium chloride; 9.45 mg benzylalcohol added as preservative. Each mL of the 10,000 USP units per mLpreparations contains: heparin sodium 10,000 USP units; 9.45 mg benzyl alcoholadded as preservative.

The preservative-free product contains(per mL): 1,000 USP units of heparin sodium and 9 mg sodium chloride.

When necessary, the pH of HEPARIN SODIUMINJECTION is adjusted with hydrochloric acid and/or sodium hydroxide. The pHrange is 5.0 to 7.5.